Could a Christian lose their salvation? Could a Christian in a time of weakness sin greatly and forsake Christ? Could a Christian in a time of deep depression deny their Lord? Could a Christian in a time of difficulty and hardship backslide spiritually and forsake Christ? Could I somehow or another loose my salvation? The Bible says: no. The thought that you could possibly lose your eternal salvation can be the cause of great anxiety. It is good to remind ourselves that our salvation is secure, not because of us, but because of God.